AMP Lab Research

Acute Exercise Study

Ultrasound

Individuals with obesity are at high risk for type 2 diabetes and cardiovascular disease. The hormone insulin rises after meals and promotes dilation of large arteries that elevate blood flow in the capillaries. This is important for delivery of oxygen and nutrients to tissues, like skeletal muscle, heart and the brain, to make energy. However, people with excess body weight do not always see this response in the presence of insulin. While exercise is known to increase blood flow and increase insulin sensitivity of muscle, it is unclear if exercise impacts heart and/or brain insulin sensitivity following a single bout of exercise. It is also unclear what is the best type of exercise. Individuals will be screened to see if they qualify and will be offered fitness, body composition, vascular health and blood flow as well as energy metabolism measures to better understand metabolic and cardiovascular health. Tests for memory and recall will also be performed. For more information, e-mail Jaclyn Dosik, M.Ed at This email address is being protected from spambots. You need JavaScript enabled to view it.. A staff member will respond to expand on information from our flyers around the community, social media, and newspapers (e.g. New Brunswick Today, Central NJ, Princetonian, etc.).

Metformin Exercise Study

person drinking OGTT

Individuals with metabolic syndrome are at high risk for type 2 diabetes and cardiovascular disease. The ideal exercise prescription for these individuals, however, remains unclear. In addition, it is unknown if people taking medication during an exercise training program have different health responses compared with people exercise alone. This question is important given that several people with metabolic syndrome are recommended to take medicine to reduce disease risk. We are particularly interest in metformin interactions with exercise since it is the most prescribed medication to regulate blood glucose levels. Our study will therefore look at the role of exercise intensity training for 16 weeks, with or without metformin, in people with metabolic syndrome. We will screen all people to see if they qualify and measure: fitness, body composition,vascular health and blood flow as well as energy metabolism to better understand the optimal treatment plan to prevent disease progression. All people will receive supervised exercise session and parking at Rutgers. For more information, e-mail Jaclyn Dosik, M.Ed at This email address is being protected from spambots. You need JavaScript enabled to view it.. A staff member will respond to expand on information from our flyers around the community, social media, and newspapers (e.g. New Brunswick Today, Central NJ, Princetonian, etc.).