Web Pages

• https://kines.rutgers.edu/wlsi/home
• https://kinesabroad.rutgers.edu
• https://eim-oc.rutgers.edu
• https://kines.rutgers.edu/medis
• https://kines.rutgers.edu/investigators
• https://medlifestyle.org

Courses Taught

01:377:205   Principles of Healthy Lifestyle
01:377:415   Lifestyles of the Mediterranean (Study Abroad - Winter/Summer)
01:377:483   Topics: Exploring the Origins of the Mediterranean Diet in Crete Island (Study Abroad - Summer)

Research Interests

a) Lifestyle interventions for the prevention and treatment of metabolic diseases

b) Metabolic regulation after severe burn injury

c) Functional significance of brown fat activation and browning of white fat

d) Regulation of VLDL-TG metabolism

e) Obesity: Epidemiology, prevention and treatment

Selected Publications

For a full publications record click here.

1. Chondronikola M, Volpi E, Børsheim E, Porter C, Annamalai P, Enerbäck S, Lidell ME, Saraf MK, Labbe SM, Hurren NM, Yfanti C, Chao T, Andersen CR, Cesani F, Hawkins H, Sidossis LS. Brown Adipose Tissue Improves Whole Body Glucose Homeostasis and Insulin Sensitivity in Humans. Diabetes. 2014 Dec; 63(12):4089-99. PMID: 25056438
2. Sidossis LS, Kajimura S. Brown and Beige Fat in Humans: Thermogenic adipocytes that control energy and glucose homeostasis. J Clin Invest. 2015 Feb; 125(2):478-86. PMID: 25642708
3. Shinoda K, Luijten IHN, Hasegawa Y, Hong H, Xue R, Sonne SiB, Chondronikola M, Kim M, Cypess AM, Nedergaard J, Sidossis LS, Tseng YH, and Kajimura S. Genetic and functional characterization of clonally-derived adult human brown adipocytes. Nature Medicine 2015 Apr; 21(4):389-94. PMID: 25774848
4. Sidossis LS, Porter C, Saraf MK, Børsheim E, Radhakrishnan RS, Chao T, Ali A, Chondronikola M, Mlcak R, Finnerty CC, Hawkins HK, Herndon DN. Browning of Subcutaneous White Adipose Tissue in Humans. Cell Metab. 2015 Aug 4; 22(2):219-27. PMID: 26244931
5. Chondronikola M, Porter C, Lidell ME, Sidossis LS. Response to comment on Chondronikola et al. Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans. (Diabetes 2014;63:4089-4099). Diabetes. 2015 Jun; 64(6):e14-5. PMID: 25999542
6. Chondronikola M, Volpi E, Børsheim E, Porter C, Saraf MK, Annamalai P, Yfanti C, Chao T, Wong D, Shinoda K, Labbė SM, Hurren NM, Cesani F, Kajimura S, Sidossis LS. Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans. Cell Metab. 2016 Jun 14; 23(6):1200-6. PMID: 27238638
7. Porter C, Tompkins RG, Finnerty CC, Sidossis LS, Suman OE, Herndon, DN. The metabolic stress response to burn trauma: current understanding and therapies. Lancet. 2016 Oct 1; 388(10052):1417-1426. PMID: 27707498
8. Chondronikola M, Porter C, Ogunbileje JO, Sidossis LS. Identification and Quantification of Human Brown Adipose Tissue. Methods Mol Biol. 2017; 1566:159-176. PMID: 28244050
9. Chondronikola M, Sidossis LS. Brown and beige fat: From molecules to physiology. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jan; 1864(1):91-103. PMID: 29859245
10. Malagaris I, Herndon DN, Polychronopoulou E, Rontoyanni VG, Andersen CR, Suman OE, burn trauma in children. Clin Nutr. 2018 Jun 4. PMID: 29907353
11. Kokkinos P, Faselis C, Franklin B, Lavie CJ, Sidossis LS, Moore H, Karasik P, Myers J.Cardiorespiratory fitness, body mass index and heart failure incidence. Eur J Heart Fail. 2019 Apr; 21(4):436-444. PMID: 30779281
12. Rahbani JF, […], Sidossis LS, Klein S, Kralli A, Cypess AM, Pedersen SB, Jessen N, Tseng YH, Gerhart-Hines Z, Seale P, Calebiro D, Giguère V, Kazak L. ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP. Nat Metab. 2022 Nov 7. PMID: 36344764
13. Diolintzi A, Panagiotakos DB, Sidossis LS. From Mediterranean diet to Mediterranean lifestyle: a narrative review. Public Health Nutr. 2019 Jun 3:1-11. [Epub ahead of print] PMID: 31156076
14. Mishra A, …., Sidossis LS, …., Ezzati M - NCD Risk Factor Collaboration (NCD-RisC). Diminishing benefits of urban living for children and adolescents' growth and development. Nature. 2023 Mar; 615(7954):874-883. PMID: 36991188; PMCID: PMC10060164. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060164/
15. Yoneshiro T, …., Sidossis LS, et al. BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. Nature. 2019 Aug 21. PMID: 31435015